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L-Acetyltyrosine
Pharmaceutical Chemistry

L-Acetyltyrosine

Formula: C11H13NO4 GOST/CAS: CAS 537-55-3

L-Acetyltyrosine (highly bioavailable amino acid derivative) is a specialized acetylated form of the essential amino acid L-tyrosine. It serves as a key raw material for the manufacturing of nootropic, neuroprotective pharmaceuticals, and premium dietary supplements. The product is a white crystalline powder with excellent water solubility. Due to its modified chemical structure, it offers significantly higher solubility and bioavailability compared to pure L-tyrosine, ensuring rapid absorption and efficient synthesis of key neurotransmitters (dopamine, norepinephrine, and epinephrine).

Applications

Pharmaceutical Manufacturing: Used as an Active Pharmaceutical Ingredient (API) in formulations for nootropic drugs, cerebrovascular enhancers, as well as complex treatments for depressive states, ADHD (attention deficit hyperactivity disorder), and chronic fatigue syndrome.
Sports Nutrition & Premium Supplements: Included in pre-workout complexes, energy boosters, and cognitive enhancement formulas designed to improve mental concentration, focus, and stamina under high stress and intense physical loads.
Parenteral & Clinical Nutrition: Applied as a highly soluble source of tyrosine in specialized intravenous (IV) infusion solutions and nutritional formulas for patients requiring metabolic support (e.g., gastrointestinal tract disorders).
Preventive & Anti-Aging Medicine: Utilized in manufacturing supplements that support thyroid function (as a precursor to the hormones thyroxine and triiodothyronine) and protect the nervous system against age-related degenerative changes.

Key Advantages

Superior Solubility and Bioavailability: Dissolves in water several times better than standard L-tyrosine. This allows for a reduced effective dose in the final formulation while maintaining maximum therapeutic response.
High Purity (Pharmaceutical Grade): Fully complies with strict international quality standards (USP/EP/BP). It guarantees the absence of heavy metals, residual solvents, and extraneous impurities.
Proven Neuroprotection: Effectively crosses the blood-brain barrier, rapidly optimizing central nervous system (CNS) function during stress, sleep deprivation, and intense mental workloads.
Technological Stability: Displays excellent compatibility with other active ingredients (B-vitamins, herbal extracts, other amino acids) and remains highly stable during encapsulation and tableting.

Storage & Transportation

  • Store in dry, cool, and well-ventilated warehouses in tightly sealed original packaging, protected from direct light.
  • Recommended temperature range: +5°C to +25°C with a relative humidity of no more than 60%.
  • Avoid exposure to direct sunlight, moisture, and co-storage with volatile or strongly odorous substances.
  • Transportation is permitted by all types of covered transport while maintaining the required temperature profile. The product is classified as non-hazardous for transport.
  • Shelf Life: 3 years from the date of manufacture.

Technical Specifications

Appearance White or almost white crystalline powder, odorless
Molecular Weight 223.23 g/mol
Assay ≥ 99.0%
Melting Point 135°C – 140°C
pH (1% aqueous solution) 2.0 – 3.5
Specific Optical Rotation +46.0° to +49.0°
Loss on Drying ≤ 0,5%

Supply info

  • Industrial fiber drums with double internal polyethylene liners of 25 kg net weight (for the powder form).
  • Hermetic aluminized foil bags of 1 kg and 5 kg for pilot lots and small-scale manufacturing.
  • Custom packaging options are available upon request for large wholesale contracts.

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