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Pharmaceutical Chemistry
Acetylcysteine
Formula:
C5H9NO3S
GOST/CAS:
CAS 616-91-1
Acetylcysteine (N-Acetyl-L-Cysteine, NAC) is a highly effective chemical raw material derived from the amino acid L-cysteine. It possesses powerful mucolytic, antioxidant, and detoxifying properties. This product serves as an indispensable primary component (Active Pharmaceutical Ingredient - API) and bio-additive for manufacturing modern pharmaceuticals, dietary supplements (nutraceuticals), and specialized therapeutic complexes within the Pharma & Health Care industry.
Applications
Pharmaceutical Industry: Acts as the primary active pharmaceutical ingredient (API) in the production of mucolytic medications (tablets, effervescent tablets, granules, syrups, and inhalation solutions). It is used to formulate drugs that reduce mucus viscosity and facilitate its clearance in respiratory tract conditions.
Dietary Supplements & Sports Nutrition: Utilized as a standalone ingredient or within complex formulations (NAC) to support the immune system, promote liver detoxification, enhance athletic endurance, and stimulate the synthesis of glutathione—the body's master intracellular antioxidant.
Medical Antidotes: Applied in the manufacturing of specific emergency antidotes used in clinical medicine for hepatoprotection during paracetamol (acetaminophen) overdoses and heavy metal poisoning.
Cosmeceuticals & Anti-Aging Products: Incorporated into specialized skincare formulations, creams, and serums due to its capability to inhibit oxidative processes and reinforce skin barrier functions.
Key Advantages
High Mucolytic Activity: Effectively cleaves the disulfide bonds of mucopolysaccharides in mucus, lowering its viscosity and promoting easier expectoration without increasing total fluid volume.
Powerful Antioxidant Effect: Directly neutralizes free radicals and serves as an immediate precursor to glutathione, providing robust cellular protection against oxidative stress.
Premium Purity Grade: Fully complies with strict international quality standards (USP/BP/EP), guaranteeing safety, exceptional stability in finished dosage forms, and the absence of foreign impurities.
Manufacturing Versatility: Exhibits excellent solubility in both water and alcohol, allowing seamless integration into diverse technological processes ranging from wet granulation to direct tablet compression.
Storage & Transportation
- Store in dry, clean, cool warehouse facilities in the tightly closed original packaging, protected from light and away from heat sources.
- Recommended storage temperature: +15°C to +25°C (in a dry place). Avoid exposure to moisture, as the product is hygroscopic.
- Avoid contact with strong oxidizing agents, alkalis, and metals (particularly copper, iron, and rubber) to prevent degradation of the active substance or alteration of its properties.
- Transportation is permissible by all types of covered transport, provided temperature regulations are maintained. The product remains stable under proper transit conditions. Shelf life — 3 years from the date of manufacture.
Technical Specifications
Appearance
White or almost white crystalline powder or colorless crystals with a weak, characteristic (sulfur-like) odor.
Assay (On Dried Basis)
98.5% – 101.0%
Melting Point
104°C – 110°C
pH (2% Aqueous Solution)
2.0 – 2.8
Loss on Drying
not more than 0.5%
Sulfated Ash
not more than 0.1%
Heavy Metals
not more than 10 ppm
Supply info
- Hermetically sealed fiber drums (cardboard drums) featuring a double internal polyethylene liner, 25 kg net weight.
- Small wholesale batches in original factory packaging are available upon request and prior agreement.