Back to Catalog
Pharmaceutical Chemistry
Ivermectin
Formula:
C48H74O14.
GOST/CAS:
CAS 70288-86-7
Ivermectin is a highly effective, broad-spectrum antiparasitic compound belonging to the class of macrocyclic lactones (avermectins). The product is a white or yellowish-white crystalline powder that is practically insoluble in water but freely soluble in organic solvents. Due to its unique mechanism of action, which blocks nerve impulse transmission in parasites, Ivermectin serves as an indispensable active pharmaceutical ingredient (API) for manufacturing advanced antiparasitic formulations in both veterinary and human medicine.
Applications
Veterinary Medicine (Primary): Used as the main active ingredient in formulations for cattle, sheep, swine, horses, and companion animals. It is exceptionally effective against nematodes (roundworms) and ectoparasites (mites, lice, and botfly larvae).
Human Pharmaceuticals: Utilized in manufacturing oral dosage forms (tablets) and topical formulations (creams/gels) for treating helminthiasis (e.g., onchocerciasis, strongyloidiasis) and dermatological conditions like demodex and rosacea.
Poultry & Aquaculture: Incorporated into complex therapeutic treatments to control endo- and ectoparasites in poultry and specific fish species.
Key Advantages
Broad-Spectrum Efficacy: Exerts a powerful lethal effect on both larval and adult stages of nematodes and arthropods at exceptionally low dosages.
Prolonged Action: Formulations based on Ivermectin remain therapeutically active within the animal's body for an extended period, ensuring reliable protection against re-infestation.
Low Toxicity to Warm-Blooded Animals: Safe for animals and humans when therapeutic doses are followed, as it does not readily cross the blood-brain barrier in mammals.
Formulation Stability: Blends excellently with various excipients, enabling the development of diverse dosage forms, including injectables, oral suspensions, pastes, and premixes.
Storage & Transportation
- Store in dry, clean, light-protected warehouses in tightly sealed original packaging at temperatures not exceeding +25°C.
- Protect from moisture and direct sunlight, as the compound is highly sensitive to light degradation.
- Transport is permitted via all types of covered transport in strict compliance with standard cargo regulations. Handle with care; use personal protective equipment (PPE) such as respirators and gloves when handling the raw powder.
- Shelf Life: 3 years from the date of manufacture.
Technical Specifications
Appearance
White or yellowish-white crystalline powder, odorless, hygroscopic.
Assay
min 95.0%
Component Ratio
min 90.0%
Related Substances (Other Avermectins)
max 5.0%
Specific Optical Rotation
-17° to -20°
Water Content
max 1.0%
Supply info
- Plastic or fiber drums with double airtight polyethylene inner liners available in 10 kg / 25 kg capacities.
- Small-scale packaging in aluminum or foil pouches of 1 kg for laboratory research and small-batch manufacturing.