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Pharmaceutical Chemistry
Resorcinol
Formula:
С6H4(OH)2
GOST/CAS:
CAS 108-46-3
Resorcinol (meta-dihydroxybenzene) is a high-purity active pharmaceutical ingredient (API) featuring pronounced antiseptic, anti-inflammatory, dermatotropic, and keratolytic properties. The product is a white to off-white crystalline powder with a characteristic odor, easily soluble in water, alcohol, and fatty oils. Due to its ability to gently exfoliate dead skin cells and suppress pathogenic microflora, resorcinol serves as an indispensable baseline component in the manufacturing of dermatological medicines, compounding pharmacy products, and therapeutic skincare or haircare formulations.
Applications
Production of Topical Dosage Forms: Utilized as an active substance in compounding ointments, pastes, and creams (often combined with salicylic acid and sulfur) for treating eczema, seborrhea, psoriasis, and fungal skin infections.
Extemporaneous Compounding: Widely used in compounding pharmacies to prepare aqueous and alcohol-based antiseptic solutions (including the well-known Castellani's paint / "Fucorcin" solution) intended for skin disinfection and drying.
Cosmeceuticals and Chemical Peels: Incorporated into professional chemical peels (such as Jessner's peel) to achieve deep skin exfoliation, target hyperpigmentation, combat acne/post-acne marks, and address age-related changes.
Trichological Products: Included in therapeutic lotions and medicated anti-dandruff shampoos to normalize sebum production and treat seborrheic alopecia while restoring scalp health.
Key Advantages
High Pharmaceutical Purity: Strictly complies with major Pharmacopoeia standards (USP/EP), remaining free from foreign impurities and heavy metals, which guarantees complete clinical safety.
Pronounced Synergistic Effect: Pairs excellently with other dermatological agents (salicylic acid, boric acid, sulfur, coal tar), enhancing the overall therapeutic efficacy of the final formulation.
Adjustable Therapeutic Action: Acts as a keratoplastic (healing) and anti-inflammatory agent at lower concentrations (0.5–2%), while shifting to a potent keratolytic (exfoliating) agent at higher concentrations (5–20%).
Adjustable Therapeutic Action: Acts as a keratoplastic (healing) and anti-inflammatory agent at lower concentrations (0.5–2%), while shifting to a potent keratolytic (exfoliating) agent at higher concentrations (5–20%).
Storage & Transportation
- Store in dry, light-protected, and well-ventilated warehouses within tightly sealed original packaging, kept away from strong oxidizing agents.
- Important: Avoid direct exposure to sunlight and moisture, as the product is prone to gradual discoloration (darkening) under light. This does not impair its primary therapeutic properties but alters its commercial appearance.
- Transportation can be conducted by all types of covered transport vehicles in full compliance with dangerous goods regulations (Classified under Class 6.1 — Toxic Substances).
- The guaranteed shelf life is 3 years from the date of manufacture.
Technical Specifications
Appearance
White or almost white crystalline powder (may develop a slight pinkish tint when exposed to light and air)
Molecular Weight
110.11 g/mol
Assay (Main Substance)
≥ 99.5%
Melting Point
109 – 111 °C
Solubility (at 20°C)
Very soluble in water (1:1) and 96% ethanol; soluble in fatty oils
Acidity / Alkalinity
The solution shows a weakly acidic or neutral reaction
Supply info
- 25 kg multi-layer paper bags lined with an inner polyethylene bag (optimized for industrial pharmaceutical manufacturing).
- 1 kg and 5 kg hermetically sealed plastic jars/bottles (tailored for compounding pharmacies, compounding facilities, and laboratories).
- Custom packaging and smaller filling options are available upon agreement with the customer.