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Pharmaceutical Chemistry
Calcium Gluconate
Formula:
C12H22CaO14
GOST/CAS:
CAS 299-28-5 / Ph.Eur., USP, BP
Calcium Gluconate (highly purified pharmaceutical substance) is a mineral supplement and an essential component acting as a key source of calcium ions for medical and veterinary applications. The product appears as a white, crystalline or granular powder, odorless and tasteless, slowly soluble in cold water and easily soluble in boiling water. Due to its high purity level and strict compliance with pharmacopoeia standards, this product serves as a core raw material for manufacturing injectable solutions, tablets, and complex formulations.
Applications
Production of Injectable Forms: Used as an Active Pharmaceutical Ingredient (API) for preparing sterile 10% solutions intended for intravenous and intramuscular administration.
Tableting and Encapsulation: Acts as a crucial component in tableting processes (including standard, chewable, or effervescent tablets), as well as a filler for hard gelatin capsules.
Veterinary and Premixes: Incorporated into medicinal products for the treatment and prevention of hypocalcemia in livestock and domestic animals, as well as in specialized feed additives.
Specialized and Infant Nutrition: Utilized in the food industry for calcium fortification in dietary, therapeutic, and infant nutrition products where maximum purity is mandatory.
Key Advantages
Pharmacopoeia Quality & Purity: Manufactured in strict compliance with GMP standards, meeting the specifications of leading pharmacopoeias (Ph.Eur., USP, BP), ensuring the complete absence of hazardous impurities and heavy metals.
High Bioavailability: Unlike inorganic calcium salts, calcium gluconate is significantly gentler on tissues at the injection site, minimizes local irritation, and is easily absorbed by the body.
Stability in Solutions: Demonstrates excellent stability during thermal sterilization (autoclaving), does not precipitate when technology guidelines are followed, and blends perfectly with various liquid media.
Safety and Hypoallergenicity: Non-toxic, free of volatile organic compounds (VOCs), completely safe for use in therapeutic doses, and satisfies stringent environmental compliance standards for pharma manufacturing.
Storage & Transportation
- Store in dry, clean, cool, and well-ventilated warehouses, inside the tightly closed original manufacturer’s packaging.
- Recommended storage temperature range is +5°C to +25°C with a relative air humidity not exceeding 70%.
- Avoid exposure to direct sunlight, moisture, and co-storage with odorous or toxic substances (the product is hygroscopic).
- Transportation is permitted by all types of covered transport in compliance with standard cargo regulations. The material is not classified as a dangerous good (non-hazardous under ADR/RID regulations).
- Shelf Life: 3 years (or up to 5 years depending on the manufacturer) from the production date, provided the original packaging remains sealed.
Technical Specifications
Appearance
White crystalline or granular powder, odorless
Molecular Weight
430.37 (g/mol} (Anhydrous) / 448.39 (g/mol} (Monohydrate)
Assay (Main Substance)
≥ 99.0%
Acidity or Alkalinity (pH)
6.0 - 7.5
Loss on Drying
≤ 1.0%
Heavy Metals Content
≤ 10 ppm
Supply info
- Standard packaging for powder form: Multi-wall paper or kraft bags with a hermetic polyethylene inner liner weighing 25 kg.
- Packaged on pallets, secured with stretch or shrink wrap to prevent any damage during transit.
- Custom delivery in specialized fiber drums is available upon client request.