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Pharmaceutical Chemistry
Sodium acetate trihydrate
Formula:
C2H3O2Na·3H2O
GOST/CAS:
CAS 6131-90-4
Sodium acetate trihydrate (pharmaceutical grade) is a high-purity chemical compound occurring as colorless crystals or a white crystalline powder with a faint acetic odor. Due to its exceptional purity level and strict compliance with international pharmacopoeia standards, this product serves as an indispensable component in the manufacturing of infusion solutions and hemodialysis fluids, and is widely utilized as a buffering agent in the biopharmaceutical industry.
Applications
Pharmaceutical Manufacturing: Used as a key active pharmaceutical ingredient (API) or excipient in the production of hemodialysis solutions and intravenous infusion fluids to correct electrolyte balance and metabolic acidosis.
Biotechnology & Biopharmaceuticals: Acts as an efficient buffering agent in fermentation processes, protein purification, and cell culture media to maintain a strictly controlled pH environment.
Laboratory & Diagnostics: An essential component of buffer solutions used in biochemical analysis, molecular biology (such as DNA precipitation), and chromatography.
Food & Cosmetics: In high-purity formulations, it can be utilized as a preservative, acidity regulator (E262), and stabilizer in specialized personal care products.
Key Advantages
Pharmacopoeia Quality: Fully complies with the stringent requirements of leading global standards (ensuring high purity and minimal heavy metal or elemental impurities).
High Solubility: Dissolves excellently in water, yielding perfectly clear, sediment-free, and unturbid solutions.
Stable Buffering Effect: Reliably stabilizes and maintains the required pH level within complex, multi-component liquid dosage forms.
Biocompatibility & Safety: Completely non-toxic when used in recommended dosages; it is readily metabolized by the body and acts as a natural participant in metabolic processes.
Storage & Transportation
- Store in dry, cool, and well-ventilated warehouses in tightly sealed original packaging, away from heat sources.
- The product is hygroscopic and tends to effloresce (lose water of crystallization) in dry air; maintaining container airtightness is critical.
- Recommended storage temperature: +5 °C to +30 °C. Protect from direct sunlight and moisture.
- Transportation is permitted via all types of covered transport while maintaining the required temperature profile. The material is non-hazardous (not regulated for transport). Shelf life is 2–3 years from the date of manufacture (depending on the packaging type).
Technical Specifications
Appearance
Colorless crystals or white crystalline powder
Molecular Weight
136.08 g/mol
Assay (Content)
≥ 99.0% - 101.0%
Density (at 20°C)
1.45 g/cm³
pH (5% aqueous solution)
7.5 – 9.2
Heavy Metals Content
≤ 0.001%
Water Solubility
1250 g/l (at 20°C)
Supply info
- Multi-layer paper bags with a polyethylene inner liner of 25 kg (ideal for powder/crystalline forms to ensure robust moisture protection).
- Special big bags (FIBC) up to 1000 kg can be supplied upon agreement for large-scale industrial manufacturing.