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Mono-Ammonium Glycyrrhizinate
Pharmaceutical Chemistry

Mono-Ammonium Glycyrrhizinate

Formula: C42H65NO16 GOST/CAS: CAS: 53956-04-0

Mono-ammonium glycyrrhizinate (ammonium glycyrrhizinate) is a highly purified active compound derived from licorice root. It possesses potent anti-inflammatory, antiviral, anti-allergic, and immunomodulatory properties. Due to its high level of purity meeting leading pharmacopeia standards (Ph. Eur., USP), this component is indispensable in the production of pharmaceuticals, specialized dietary supplements, and cosmeceuticals.

Applications

Pharmaceutical Industry: Used as an API (Active Pharmaceutical Ingredient) in cough syrups and tablets (as an expectorant), antiviral, and hepatoprotective medicines, as well as topical ointments for treating dermatitis and eczema.
Dietary Supplements & Sports Nutrition: Included in formulations designed for immune support, gastrointestinal health, and adrenal regulation. It also serves as a premium, low-glycemic natural sweetener (50–100 times sweeter than sucrose).
Cosmeceuticals & Personal Care: Utilized in toothpaste formulations to reduce gum bleeding, and in creams or serums for sensitive skin to relieve irritation, itching, and redness.

Key Advantages

High Biological Activity: Effectively suppresses inflammatory processes at the cellular level, stimulates interferon production, and protects liver cells (hepatoprotective effect).
Pharmaceutical Purity: Undergoes a multi-stage purification process, free from foreign impurities, toxic solvents, and heavy metals, guaranteeing high safety of application.
Synergistic Effect: Pairs excellently with other herbal extracts, vitamins, and antibiotics, enhancing their therapeutic efficacy.
Natural Origin: The product is 100% natural, biodegradable, and environmentally safe when disposed of according to regulations.

Storage & Transportation

  • Store in dry, cool, and light-protected warehouses in tightly closed original packaging.
  • Recommended storage temperature: +15Β°C to +25Β°C. Avoid exposure to high humidity (the product is hygroscopic).
  • Transportation is permitted by all types of covered transport in compliance with general cargo transportation regulations. The product is classified as non-hazardous.
  • Shelf Life: 3 years from the date of manufacture.

Technical Specifications

Appearance White or almost white crystalline powder
Odor & Taste Faint characteristic odor with a strong sweet taste
Molecular Weight 839.97 g/mol
Assay (Main Substance) β‰₯ 98.0%
Solubility Soluble in water, sparingly soluble in ethanol
pH (1% aqueous solution) 5.5 – 6.5

Supply info

  • Multi-wall paper bags or fiber drums with a double polyethylene inner liner available in 10 kg and 25 kg capacities (optimized for protecting the powder from moisture and maintaining airtightness).
  • Custom packaging in small 1 kg containers is available for laboratory testing and pilot batches.

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