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Pharmaceutical Chemistry
Citicoline Sodium
Formula:
C14H25N4NaO11P2
GOST/CAS:
CAS: 33818-15-4
Citicoline Sodium (cytidine 5'-diphocholine sodium salt) is a highly purified, water-soluble macromonomer/compound that serves as a key raw material and intermediate in the biosynthesis of structural phospholipids in cellular membranes (particularly phosphatidylcholine). The product is a white or almost white crystalline powder, odorless, and exhibits high hygroscopicity. Due to its superior bioavailability and clinically proven efficacy, Citicoline Sodium is widely utilized as an Active Pharmaceutical Ingredient (API) and a foundational component for manufacturing nootropic drugs, neuroprotectants, and specialized dietary supplements (nutraceuticals) designed to support cognitive function.
Applications
Pharmaceutical Manufacturing: Functions as a core Active Pharmaceutical Ingredient (API) for the synthesis of nootropic, neurometabolic, and neuroprotective medications (injectable solutions, oral solutions, and tablets).
Dietary Supplements (Nutraceuticals): Utilized in complex formulas and standalone supplements aimed at enhancing memory, focus, mental clarity, and overall brain health.
Sports Nutrition & Functional Beverages: Incorporated into premium pre-workout formulations and "nootropic" drinks to elevate focus, motor coordination, and cognitive endurance in athletes.
Specialized & Geriatric Nutrition: Formulated into dietary products aimed at preventing age-related cognitive decline and supporting the nervous system in the elderly.
Key Advantages
High Bioavailability & Efficacy: Highly absorbable upon oral administration, breaking down into choline and cytidine, which readily cross the blood-brain barrier to stimulate acetylcholine synthesis.
Comprehensive Neuroprotective Action: Helps repair and rebuild damaged neuronal cell membranes, inhibits the activity of certain phospholipases, and prevents the excessive formation of free radicals.
Broad Technological Compatibility: Highly soluble in water and stable across a wide pH range, allowing for easy integration into any liquid or solid dosage forms (capsules, tablets, syrups, or ampoules).
Safety and Pure Quality: Features an excellent safety profile with low toxicity, manufactured under strict GMP standards, and is free from foreign impurities, heavy metals, or residual organic solvents.
Storage & Transportation
- Store in dry, cool, and well-ventilated warehouse premises, protected from light in the tightly sealed original manufacturer’s packaging.
- Avoid direct sunlight, exposure to moisture, and high temperatures (ideally below 25°C), as the product is highly prone to caking (agglomeration) due to its hygroscopic nature.
- Transportation is permissible via all types of covered transport in accordance with standard freight regulations. The material is classified as non-hazardous cargo. Shelf life is 2–3 years (depending on the manufacturer's packaging).
Frequently bought together
Technical Specifications
Appearance
White or almost white crystalline powder, hygroscopic
Molecular Weight
~ 510.31 g/mol
Assay (Purity via HPLC)
≥ 98.0% – 102.0% (on the dried basis)
Loss on Drying (Moisture Content)
Not more than 5.0%
pH (10% Aqueous Solution)
6.0 – 7.5
Heavy Metals
≤ 20 ppm
Supply info
- Sealed double-layer plastic bags placed within fiber drums (cardboard drums) with a net weight of 25 kg.
- Small-scale packaging (aluminum foil bags) of 1 kg, 5 kg, or 10 kg available upon custom agreement with the customer.