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FDP (Fructose-1,6-Diphosphate)
Pharmaceutical Chemistry

FDP (Fructose-1,6-Diphosphate)

Formula: C₆H₁₄O₁₂P₂ GOST/CAS: CAS 488-35-7

FDP (Fructose-1,6-Diphosphate Trisodium Salt) is a highly purified biochemical macromonomer and a key metabolic intermediate. It serves as the primary active pharmaceutical ingredient (API) for the production of intravenous and oral medications, as well as specialized dietary supplements. The product is a white or almost white crystalline powder, highly soluble in water. Due to its unique ability to optimize cellular metabolism under hypoxic conditions, FDP is an indispensable raw material for formulating cardioprotectors, anti-ischemic agents, and sports medicine products.

Applications

Pharmaceutical Manufacturing: Acts as the core Active Pharmaceutical Ingredient (API) for synthesizing infusion solutions and powders used to treat myocardial ischemia, acute myocardial infarction, and shock conditions.
Sports Medicine & Dietary Supplements: Utilized in complex recovery formulations to boost physical endurance, accelerate ATP regeneration, and protect muscle tissue from hypoxic stress.
Clinical Nutrition: Incorporated into specialized nutritional formulas for critical care patients or those undergoing intensive recovery following cardiothoracic surgeries.
Laboratory Research: Used as a premium biochemical reagent in molecular biology and biotechnological studies evaluating cellular metabolic pathways.

Key Advantages

High Metabolic Activity: FDP bypasses the energy-consuming initial steps of glycolysis, directly entering the metabolic cycle to allow cells to generate ATP even under oxygen-depleted (ischemic) conditions.
Purity and Stability: Manufactured in strict compliance with GMP standards, ensuring a predictable solubility profile and minimizing related substances/impurities.
Cardio- and Cytoprotection: Effectively shields cell membranes against lipid peroxidation and helps stabilize intracellular potassium levels during stress.
Eco-Friendly & Biocompatible: A completely biocompatible, endogenous compound. It is non-toxic, free from mutagenic effects, and safe for the environment when disposed of properly.

Storage & Transportation

  • Store in dry, cool, and light-protected warehouses in the tightly sealed original packaging.
  • Recommended Temperature: +2°C to +8°C (Depending on the manufacturer's specification, storage below 25°C in a moisture-protected area may be permissible).
  • Protect from direct sunlight and humidity, as the product is highly hygroscopic.
  • Transportable by all types of covered transport while strictly maintaining the required temperature control. The material is classified as non-hazardous for transport. Shelf life — 2 years.

Technical Specifications

Appearance White or almost white crystalline powder
Molecular Weight ~406.06 g/mol (for Trisodium Salt)
Assay (Main Component) 98.0% – 102.0%
Moisture Content ≤ 5.0%
pH (5% aqueous solution) 5.5 – 6.5
Heavy Metals ≤ 10 ppm

Supply info

  • Industrial Scale: 10 kg / 25 kg multi-layer pharmaceutical-grade paper bags or kraft drums with a double polyethylene inner liner.
  • Pilot/Lab Scale: 1 kg / 5 kg hermetically sealed aluminum foil pouches for R&D and pilot batch production.

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