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L-Arginine Hydrochloride
Pharmaceutical Chemistry

L-Arginine Hydrochloride

Formula: C₆H₁₅ClN₄O₂ GOST/CAS: CAS 1119-34-2

L-Arginine Hydrochloride is the hydrochloride salt of the essential (conditionally essential) amino acid L-arginine, characterized by a high degree of purity and excellent water solubility. The product presents as a white crystalline powder or colorless crystals with a faint, characteristic odor. Due to its high bioavailability and stability, L-Arginine HCl serves as a key raw material component in the pharmaceutical, food, and cosmetic industries, as well as in the production of specialized sports nutrition and feed additives.

Applications

Pharmaceutical Manufacturing: Utilized as an Active Pharmaceutical Ingredient (API) for the synthesis of drugs that improve myocardial metabolism, hepatoprotectors, parenteral nutrition solutions, and detoxifying agents.
Supplements & Sports Nutrition: Serves as a core component in pre-workout complexes and supplements (nitric oxide boosters) aimed at enhancing muscle pump, endurance, and accelerating recovery.
Food Industry: Applied as a fortifying additive and functional ingredient in dietary food products and beverages.
Cosmeceuticals & Personal Care: Used in formulations for anti-aging cosmetics, creams designed to improve skin microcirculation, and restorative hair care products.

Key Advantages

High Bioavailability & Stability: The hydrochloride form (HCl) is significantly more stable than free-base L-arginine, dissolves faster in water, and is more readily absorbed by the body.
Stimulation of Nitric Oxide (NO) Synthesis: Effectively dilates blood vessels, improving blood flow and the transport of nutrients to tissues and organs.
High Purity Level: The product fully complies with strict international quality standards (USP/EP/BP), guaranteeing the absence of foreign impurities and ensuring safety in use.
Mild pH Profile: Unlike free-base arginine, which has a highly alkaline reaction, the hydrochloride form features a more neutral pH in solutions, simplifying the technological process of finished product manufacturing.

Storage & Transportation

  • Store in dry, cool, light-protected, and well-ventilated warehouse premises in tightly sealed original packaging.
  • Avoid exposure to direct sunlight, moisture, and high temperatures. The product is hygroscopic.
  • Transportation is permissible by all types of covered transport in accordance with standard cargo regulations. The material is classified as non-hazardous for transport. Shelf life — 2-3 years (depending on the manufacturer).

Technical Specifications

Appearance White crystalline powder or colorless crystals
Molecular Weight 210.66 g/mol
Assay (Main Substance) Not less than 99.0%
pH (5% aqueous solution) 4.7 – 6.2
Loss on Drying Not more than 0.5%
Residue on Ignition Not more than 0.1%
Heavy Metals (Pb) Not more than 10 ppm

Supply info

  • Fiber drums (kraft drums) with a double internal polyethylene liner, 25 kg net weight.
  • Cardboard boxes with a protective inner liner, 25 kg net weight (upon agreement with the customer).

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Merit Chemicals